SMALL MOLECULE DRUG DISCOVERY TARGETING THE JAK-STAT PATHWAY

Small molecule drug discovery targeting the JAK-STAT pathway

The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway functions as a central hub for transmitting signals from more than 50 cytokines, playing a pivotal role in maintaining hematopoiesis, immune balance, and tissue homeostasis.Dysregulation of this pathway has been implicated in various diseases, including immunodefic

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SDR-Fi-Z: A Wireless Local Area Network-Fingerprinting-Based Indoor Positioning Method for E911 Vertical Accuracy Mandate

The Enhanced 911 (E911) mandate of the Federal Communications Commission (FCC) drives the evolution of indoor Stove Clockwork Timer three-dimensional (3D) location/positioning services for emergency calls.Many indoor localization systems exploit location-dependent wireless signaling signatures, often called fingerprints, and machine learning techni

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